Early mortality in lung cancer: French prospective multicentre observational study
Identifieur interne : 000067 ( France/Analysis ); précédent : 000066; suivant : 000068Early mortality in lung cancer: French prospective multicentre observational study
Auteurs : Michel Grivaux ; Didier Debieuvre [France] ; Dominique Herman [France] ; Christine Lemonnier [France] ; Jean-Michel Marcos [France] ; Jacky Crequit [France] ; Sylvie Vuillermoz-Blas [France] ; Patricia Barre [France] ; Marie Saillour [France] ; Francis Martin [France]Source :
- BMC Pulmonary Medicine [ 1471-2466 ] ; 2016.
Abstract
Despite the progress seen in the last decade in diagnosis and treatment, lung cancer has still a bad prognosis and a substantial number of patients died within the weeks following diagnosis. The objective of this study was to quantify early mortality in lung cancer, to identify patients who are at high risk of early decease, and to describe their management in a real world.
Prospective observational study including consecutively all adult patients managed for primary lung cancer histologically or cytologically diagnosed in 2010 in the respiratory medicine department of one of the participating French general hospitals. Patients and cancer characteristics and first therapeutic strategy were collected at diagnosis. Dates of death were obtained from investigators or town council of the patient’s birth place. All fatal cases were considered regardless of the cause of the death. Multivariate logistic regression model was used to determine the factors significantly and independently associated with death at 1 and 3 months.
Seven thousand fifty-one patients from 104 centres were included in the study. Vital status was obtained for 6,981 patients. Respectively, 678 (9.7 %) and 1,621 (23.2 %) of the 6,981 patients with available data died within 1 and 3 months following diagnosis. As compared with the other patients, they were significantly older and frailer (based on performance status [PS] and recent weight loss) and more frequently reported stage IV tumour. Overall, 64.5 % (1 month) and 42.8 % (3 months) of patients had no cancer therapy and less than 1 % were included in a therapeutic trial.
About one in four patients died within 3 months following lung cancer diagnosis. Early mortality mainly involves frail patients with advanced cancer and is associated with lack of cancer therapy. This supports the need for early diagnosis and clinical trials in this population. Reducing early mortality to give supplementary time to patients to organise the future is a major challenge for 21st century physicians.
Url:
DOI: 10.1186/s12890-016-0205-5
PubMed: 27039176
PubMed Central: 4818853
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000039
- to stream Pmc, to step Curation: 000037
- to stream Pmc, to step Checkpoint: 000010
- to stream Ncbi, to step Merge: 000533
- to stream Ncbi, to step Curation: 000533
- to stream Ncbi, to step Checkpoint: 000533
- to stream Main, to step Merge: 000068
- to stream Main, to step Curation: 000069
- to stream Main, to step Exploration: 000069
- to stream France, to step Extraction: 000067
Links to Exploration step
PMC:4818853Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Early mortality in lung cancer: French prospective multicentre observational study</title>
<author><name sortKey="Grivaux, Michel" sort="Grivaux, Michel" uniqKey="Grivaux M" first="Michel" last="Grivaux">Michel Grivaux</name>
<affiliation><nlm:aff id="Aff1">Service de pneumologie, Centre hospitalier, BP 218, 6-8 rue Saint Fiacre, Meaux, 77104 Cedex France</nlm:aff>
<wicri:noCountry code="subfield">77104 Cedex France</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Debieuvre, Didier" sort="Debieuvre, Didier" uniqKey="Debieuvre D" first="Didier" last="Debieuvre">Didier Debieuvre</name>
<affiliation wicri:level="1"><nlm:aff id="Aff2">Service de pneumologie, Hôpital Emile Muller, Mulhouse, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Hôpital Emile Muller, Mulhouse</wicri:regionArea>
<placeName><settlement type="city">Mulhouse</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Herman, Dominique" sort="Herman, Dominique" uniqKey="Herman D" first="Dominique" last="Herman">Dominique Herman</name>
<affiliation wicri:level="1"><nlm:aff id="Aff3">Service de pneumologie, Hôpital Pierre Beregovoy, Nevers, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Hôpital Pierre Beregovoy, Nevers</wicri:regionArea>
<placeName><settlement type="city">Nevers</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lemonnier, Christine" sort="Lemonnier, Christine" uniqKey="Lemonnier C" first="Christine" last="Lemonnier">Christine Lemonnier</name>
<affiliation wicri:level="1"><nlm:aff id="Aff4">Service de pneumologie, Centre hospitalier, Auxerre, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Centre hospitalier, Auxerre</wicri:regionArea>
<placeName><settlement type="city">Auxerre</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Marcos, Jean Michel" sort="Marcos, Jean Michel" uniqKey="Marcos J" first="Jean-Michel" last="Marcos">Jean-Michel Marcos</name>
<affiliation wicri:level="1"><nlm:aff id="Aff5">Service de pneumologie, Centre hospitalier, Libourne, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Centre hospitalier, Libourne</wicri:regionArea>
<placeName><settlement type="city">Libourne</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Crequit, Jacky" sort="Crequit, Jacky" uniqKey="Crequit J" first="Jacky" last="Crequit">Jacky Crequit</name>
<affiliation wicri:level="1"><nlm:aff id="Aff6">Service de pneumologie, Hôpital Laënnec , Creil, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Hôpital Laënnec , Creil</wicri:regionArea>
<wicri:noRegion>Creil</wicri:noRegion>
<wicri:noRegion>Creil</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vuillermoz Blas, Sylvie" sort="Vuillermoz Blas, Sylvie" uniqKey="Vuillermoz Blas S" first="Sylvie" last="Vuillermoz-Blas">Sylvie Vuillermoz-Blas</name>
<affiliation wicri:level="1"><nlm:aff id="Aff7">Service de pneumologie, Hôpital St-Joseph-St-Luc , Lyon, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Hôpital St-Joseph-St-Luc , Lyon</wicri:regionArea>
<placeName><settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Barre, Patricia" sort="Barre, Patricia" uniqKey="Barre P" first="Patricia" last="Barre">Patricia Barre</name>
<affiliation wicri:level="1"><nlm:aff id="Aff8">Service de pneumologie, Centre hospitalier, Cahors, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Centre hospitalier, Cahors</wicri:regionArea>
<placeName><settlement type="city">Cahors</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Saillour, Marie" sort="Saillour, Marie" uniqKey="Saillour M" first="Marie" last="Saillour">Marie Saillour</name>
<affiliation wicri:level="1"><nlm:aff id="Aff9">Service de pneumologie, Centre hospitalier, Nanterre, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Centre hospitalier, Nanterre</wicri:regionArea>
<placeName><settlement type="city">Nanterre</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Martin, Francis" sort="Martin, Francis" uniqKey="Martin F" first="Francis" last="Martin">Francis Martin</name>
<affiliation wicri:level="1"><nlm:aff id="Aff10">Pneumologie et Pathologies du sommeil, Centre hospitalier Intercommunal Compiègne-Noyon, Compiègne, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Pneumologie et Pathologies du sommeil, Centre hospitalier Intercommunal Compiègne-Noyon, Compiègne</wicri:regionArea>
<placeName><settlement type="city">Compiègne</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">27039176</idno>
<idno type="pmc">4818853</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818853</idno>
<idno type="RBID">PMC:4818853</idno>
<idno type="doi">10.1186/s12890-016-0205-5</idno>
<date when="2016">2016</date>
<idno type="wicri:Area/Pmc/Corpus">000039</idno>
<idno type="wicri:Area/Pmc/Curation">000037</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000010</idno>
<idno type="wicri:Area/Ncbi/Merge">000533</idno>
<idno type="wicri:Area/Ncbi/Curation">000533</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000533</idno>
<idno type="wicri:Area/Main/Merge">000068</idno>
<idno type="wicri:Area/Main/Curation">000069</idno>
<idno type="wicri:Area/Main/Exploration">000069</idno>
<idno type="wicri:Area/France/Extraction">000067</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Early mortality in lung cancer: French prospective multicentre observational study</title>
<author><name sortKey="Grivaux, Michel" sort="Grivaux, Michel" uniqKey="Grivaux M" first="Michel" last="Grivaux">Michel Grivaux</name>
<affiliation><nlm:aff id="Aff1">Service de pneumologie, Centre hospitalier, BP 218, 6-8 rue Saint Fiacre, Meaux, 77104 Cedex France</nlm:aff>
<wicri:noCountry code="subfield">77104 Cedex France</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Debieuvre, Didier" sort="Debieuvre, Didier" uniqKey="Debieuvre D" first="Didier" last="Debieuvre">Didier Debieuvre</name>
<affiliation wicri:level="1"><nlm:aff id="Aff2">Service de pneumologie, Hôpital Emile Muller, Mulhouse, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Hôpital Emile Muller, Mulhouse</wicri:regionArea>
<placeName><settlement type="city">Mulhouse</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Herman, Dominique" sort="Herman, Dominique" uniqKey="Herman D" first="Dominique" last="Herman">Dominique Herman</name>
<affiliation wicri:level="1"><nlm:aff id="Aff3">Service de pneumologie, Hôpital Pierre Beregovoy, Nevers, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Hôpital Pierre Beregovoy, Nevers</wicri:regionArea>
<placeName><settlement type="city">Nevers</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Lemonnier, Christine" sort="Lemonnier, Christine" uniqKey="Lemonnier C" first="Christine" last="Lemonnier">Christine Lemonnier</name>
<affiliation wicri:level="1"><nlm:aff id="Aff4">Service de pneumologie, Centre hospitalier, Auxerre, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Centre hospitalier, Auxerre</wicri:regionArea>
<placeName><settlement type="city">Auxerre</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Marcos, Jean Michel" sort="Marcos, Jean Michel" uniqKey="Marcos J" first="Jean-Michel" last="Marcos">Jean-Michel Marcos</name>
<affiliation wicri:level="1"><nlm:aff id="Aff5">Service de pneumologie, Centre hospitalier, Libourne, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Centre hospitalier, Libourne</wicri:regionArea>
<placeName><settlement type="city">Libourne</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Crequit, Jacky" sort="Crequit, Jacky" uniqKey="Crequit J" first="Jacky" last="Crequit">Jacky Crequit</name>
<affiliation wicri:level="1"><nlm:aff id="Aff6">Service de pneumologie, Hôpital Laënnec , Creil, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Hôpital Laënnec , Creil</wicri:regionArea>
<wicri:noRegion>Creil</wicri:noRegion>
<wicri:noRegion>Creil</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vuillermoz Blas, Sylvie" sort="Vuillermoz Blas, Sylvie" uniqKey="Vuillermoz Blas S" first="Sylvie" last="Vuillermoz-Blas">Sylvie Vuillermoz-Blas</name>
<affiliation wicri:level="1"><nlm:aff id="Aff7">Service de pneumologie, Hôpital St-Joseph-St-Luc , Lyon, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Hôpital St-Joseph-St-Luc , Lyon</wicri:regionArea>
<placeName><settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Barre, Patricia" sort="Barre, Patricia" uniqKey="Barre P" first="Patricia" last="Barre">Patricia Barre</name>
<affiliation wicri:level="1"><nlm:aff id="Aff8">Service de pneumologie, Centre hospitalier, Cahors, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Centre hospitalier, Cahors</wicri:regionArea>
<placeName><settlement type="city">Cahors</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Saillour, Marie" sort="Saillour, Marie" uniqKey="Saillour M" first="Marie" last="Saillour">Marie Saillour</name>
<affiliation wicri:level="1"><nlm:aff id="Aff9">Service de pneumologie, Centre hospitalier, Nanterre, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de pneumologie, Centre hospitalier, Nanterre</wicri:regionArea>
<placeName><settlement type="city">Nanterre</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Martin, Francis" sort="Martin, Francis" uniqKey="Martin F" first="Francis" last="Martin">Francis Martin</name>
<affiliation wicri:level="1"><nlm:aff id="Aff10">Pneumologie et Pathologies du sommeil, Centre hospitalier Intercommunal Compiègne-Noyon, Compiègne, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Pneumologie et Pathologies du sommeil, Centre hospitalier Intercommunal Compiègne-Noyon, Compiègne</wicri:regionArea>
<placeName><settlement type="city">Compiègne</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">BMC Pulmonary Medicine</title>
<idno type="eISSN">1471-2466</idno>
<imprint><date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Background</title>
<p>Despite the progress seen in the last decade in diagnosis and treatment, lung cancer has still a bad prognosis and a substantial number of patients died within the weeks following diagnosis. The objective of this study was to quantify early mortality in lung cancer, to identify patients who are at high risk of early decease, and to describe their management in a real world.</p>
</sec>
<sec><title>Methods</title>
<p>Prospective observational study including consecutively all adult patients managed for primary lung cancer histologically or cytologically diagnosed in 2010 in the respiratory medicine department of one of the participating French general hospitals. Patients and cancer characteristics and first therapeutic strategy were collected at diagnosis. Dates of death were obtained from investigators or town council of the patient’s birth place. All fatal cases were considered regardless of the cause of the death. Multivariate logistic regression model was used to determine the factors significantly and independently associated with death at 1 and 3 months.</p>
</sec>
<sec><title>Results</title>
<p>Seven thousand fifty-one patients from 104 centres were included in the study. Vital status was obtained for 6,981 patients. Respectively, 678 (9.7 %) and 1,621 (23.2 %) of the 6,981 patients with available data died within 1 and 3 months following diagnosis. As compared with the other patients, they were significantly older and frailer (based on performance status [PS] and recent weight loss) and more frequently reported stage IV tumour. Overall, 64.5 % (1 month) and 42.8 % (3 months) of patients had no cancer therapy and less than 1 % were included in a therapeutic trial.</p>
</sec>
<sec><title>Conclusion</title>
<p>About one in four patients died within 3 months following lung cancer diagnosis. Early mortality mainly involves frail patients with advanced cancer and is associated with lack of cancer therapy. This supports the need for early diagnosis and clinical trials in this population. Reducing early mortality to give supplementary time to patients to organise the future is a major challenge for 21<sup>st</sup>
century physicians.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Walters, S" uniqKey="Walters S">S Walters</name>
</author>
<author><name sortKey="Maringe, C" uniqKey="Maringe C">C Maringe</name>
</author>
<author><name sortKey="Coleman, Mp" uniqKey="Coleman M">MP Coleman</name>
</author>
<author><name sortKey="Peake, Md" uniqKey="Peake M">MD Peake</name>
</author>
<author><name sortKey="Butler, J" uniqKey="Butler J">J Butler</name>
</author>
<author><name sortKey="Young, N" uniqKey="Young N">N Young</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="O Owd, El" uniqKey="O Owd E">EL O’Dowd</name>
</author>
<author><name sortKey="Mckeever, Tm" uniqKey="Mckeever T">TM McKeever</name>
</author>
<author><name sortKey="Baldwin, Dr" uniqKey="Baldwin D">DR Baldwin</name>
</author>
<author><name sortKey="Anwar, S" uniqKey="Anwar S">S Anwar</name>
</author>
<author><name sortKey="Powell, Ha" uniqKey="Powell H">HA Powell</name>
</author>
<author><name sortKey="Gibson, Je" uniqKey="Gibson J">JE Gibson</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Grivaux, M" uniqKey="Grivaux M">M Grivaux</name>
</author>
<author><name sortKey="Locher, C" uniqKey="Locher C">C Locher</name>
</author>
<author><name sortKey="Bombaron, P" uniqKey="Bombaron P">P Bombaron</name>
</author>
<author><name sortKey="Collon, T" uniqKey="Collon T">T Collon</name>
</author>
<author><name sortKey="Coetmeur, D" uniqKey="Coetmeur D">D Coëtmeur</name>
</author>
<author><name sortKey="Dayen, C" uniqKey="Dayen C">C Dayen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Medarov, B" uniqKey="Medarov B">B Medarov</name>
</author>
<author><name sortKey="Challa, Tr" uniqKey="Challa T">TR Challa</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Locher, C" uniqKey="Locher C">C Locher</name>
</author>
<author><name sortKey="Debieuvre, D" uniqKey="Debieuvre D">D Debieuvre</name>
</author>
<author><name sortKey="Coetmeur, D" uniqKey="Coetmeur D">D Coëtmeur</name>
</author>
<author><name sortKey="Goupil, F" uniqKey="Goupil F">F Goupil</name>
</author>
<author><name sortKey="Molinier, O" uniqKey="Molinier O">O Molinier</name>
</author>
<author><name sortKey="Collon, T" uniqKey="Collon T">T Collon</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Blanchon, F" uniqKey="Blanchon F">F Blanchon</name>
</author>
<author><name sortKey="Grivaux, M" uniqKey="Grivaux M">M Grivaux</name>
</author>
<author><name sortKey="Asselain, B" uniqKey="Asselain B">B Asselain</name>
</author>
<author><name sortKey="Lebas, Fx" uniqKey="Lebas F">FX Lebas</name>
</author>
<author><name sortKey="Orlando, Jp" uniqKey="Orlando J">JP Orlando</name>
</author>
<author><name sortKey="Piquet, J" uniqKey="Piquet J">J Piquet</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Myers, J" uniqKey="Myers J">J Myers</name>
</author>
<author><name sortKey="Lata, K" uniqKey="Lata K">K Lata</name>
</author>
<author><name sortKey="Chowdhury, S" uniqKey="Chowdhury S">S Chowdhury</name>
</author>
<author><name sortKey="Mcauley, P" uniqKey="Mcauley P">P McAuley</name>
</author>
<author><name sortKey="Jain, N" uniqKey="Jain N">N Jain</name>
</author>
<author><name sortKey="Froelicher, V" uniqKey="Froelicher V">V Froelicher</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Myrskyl, M" uniqKey="Myrskyl M">M Myrskylä</name>
</author>
<author><name sortKey="Chang, Vw" uniqKey="Chang V">VW Chang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Demedts, Ik" uniqKey="Demedts I">IK Demedts</name>
</author>
<author><name sortKey="Vermaelen, Ky" uniqKey="Vermaelen K">KY Vermaelen</name>
</author>
<author><name sortKey="Van Meerbeeck, Jp" uniqKey="Van Meerbeeck J">JP van Meerbeeck</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Aarts, Mj" uniqKey="Aarts M">MJ Aarts</name>
</author>
<author><name sortKey="Van Den Borne, Be" uniqKey="Van Den Borne B">BE van den Borne</name>
</author>
<author><name sortKey="Biesma, B" uniqKey="Biesma B">B Biesma</name>
</author>
<author><name sortKey="Kloover, Js" uniqKey="Kloover J">JS Kloover</name>
</author>
<author><name sortKey="Aerts, Jg" uniqKey="Aerts J">JG Aerts</name>
</author>
<author><name sortKey="Lemmens, Ve" uniqKey="Lemmens V">VE Lemmens</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Nieder, C" uniqKey="Nieder C">C Nieder</name>
</author>
<author><name sortKey="Angelo, K" uniqKey="Angelo K">K Angelo</name>
</author>
<author><name sortKey="Haukland, E" uniqKey="Haukland E">E Haukland</name>
</author>
<author><name sortKey="Pawinski, A" uniqKey="Pawinski A">A Pawinski</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Pezzi, Cm" uniqKey="Pezzi C">CM Pezzi</name>
</author>
<author><name sortKey="Mallin, K" uniqKey="Mallin K">K Mallin</name>
</author>
<author><name sortKey="Mendez, As" uniqKey="Mendez A">AS Mendez</name>
</author>
<author><name sortKey="Greer Gay, E" uniqKey="Greer Gay E">E Greer Gay</name>
</author>
<author><name sortKey="Putnam, Jb" uniqKey="Putnam J">JB Putnam</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Morere, Jf" uniqKey="Morere J">JF Morere</name>
</author>
<author><name sortKey="Brechot, Jm" uniqKey="Brechot J">JM Brechot</name>
</author>
<author><name sortKey="Westeel, V" uniqKey="Westeel V">V Westeel</name>
</author>
<author><name sortKey="Gounant, V" uniqKey="Gounant V">V Gounant</name>
</author>
<author><name sortKey="Lebeau, B" uniqKey="Lebeau B">B Lebeau</name>
</author>
<author><name sortKey="Vaylet, F" uniqKey="Vaylet F">F Vaylet</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>France</li>
</country>
<settlement><li>Auxerre</li>
<li>Cahors</li>
<li>Compiègne</li>
<li>Libourne</li>
<li>Lyon</li>
<li>Mulhouse</li>
<li>Nanterre</li>
<li>Nevers</li>
</settlement>
</list>
<tree><noCountry><name sortKey="Grivaux, Michel" sort="Grivaux, Michel" uniqKey="Grivaux M" first="Michel" last="Grivaux">Michel Grivaux</name>
</noCountry>
<country name="France"><noRegion><name sortKey="Debieuvre, Didier" sort="Debieuvre, Didier" uniqKey="Debieuvre D" first="Didier" last="Debieuvre">Didier Debieuvre</name>
</noRegion>
<name sortKey="Barre, Patricia" sort="Barre, Patricia" uniqKey="Barre P" first="Patricia" last="Barre">Patricia Barre</name>
<name sortKey="Crequit, Jacky" sort="Crequit, Jacky" uniqKey="Crequit J" first="Jacky" last="Crequit">Jacky Crequit</name>
<name sortKey="Herman, Dominique" sort="Herman, Dominique" uniqKey="Herman D" first="Dominique" last="Herman">Dominique Herman</name>
<name sortKey="Lemonnier, Christine" sort="Lemonnier, Christine" uniqKey="Lemonnier C" first="Christine" last="Lemonnier">Christine Lemonnier</name>
<name sortKey="Marcos, Jean Michel" sort="Marcos, Jean Michel" uniqKey="Marcos J" first="Jean-Michel" last="Marcos">Jean-Michel Marcos</name>
<name sortKey="Martin, Francis" sort="Martin, Francis" uniqKey="Martin F" first="Francis" last="Martin">Francis Martin</name>
<name sortKey="Saillour, Marie" sort="Saillour, Marie" uniqKey="Saillour M" first="Marie" last="Saillour">Marie Saillour</name>
<name sortKey="Vuillermoz Blas, Sylvie" sort="Vuillermoz Blas, Sylvie" uniqKey="Vuillermoz Blas S" first="Sylvie" last="Vuillermoz-Blas">Sylvie Vuillermoz-Blas</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/France/explor/LeHavreV1/Data/France/Analysis
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000067 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/France/Analysis/biblio.hfd -nk 000067 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/France |area= LeHavreV1 |flux= France |étape= Analysis |type= RBID |clé= PMC:4818853 |texte= Early mortality in lung cancer: French prospective multicentre observational study }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/France/Analysis/RBID.i -Sk "pubmed:27039176" \ | HfdSelect -Kh $EXPLOR_AREA/Data/France/Analysis/biblio.hfd \ | NlmPubMed2Wicri -a LeHavreV1
This area was generated with Dilib version V0.6.25. |